New pharmaceutical plants in the US
We track 69 large pharmaceutical plant projects announced in the US since 2021, with $78 billion and 24,496 jobs announced in total. 11 are under construction, 6 are operating and 52 are announced only.
- Projects
- 69
- Announced
- $78B
- Jobs announced
- 24,496
- States
- 24
- Revised
- November 11, 2026
The biggest projects
Lebanon API manufacturing site (LEAP district) in Lebanon, Indiana: $9.0 billion announced with 900 jobs, now under construction. Houston API facility, Generation Park in Houston, Texas: $6.5 billion announced with 615 jobs, now under construction. Huntsville API manufacturing plant (Greenbrier South) in Huntsville, Alabama: $6.0 billion announced with 450 jobs, now announced.
Every project we track
| Project | Status | Announced |
|---|---|---|
| Lebanon API manufacturing site (LEAP district)Eli Lilly and Company, Lebanon, IN | Under construction | $9.0B900 jobs |
| Houston API facility, Generation ParkEli Lilly and Company, Houston, TX | Under construction | $6.5B615 jobs |
| Huntsville API manufacturing plant (Greenbrier South)Eli Lilly and Company, Huntsville, AL | Announced | $6.0B450 jobs |
| Richmond-area ADC / API facilityEli Lilly and Company, Goochland County (West Creek), VA | Under construction | $5.0B650 jobs |
| Virginia drug substance facility (Rivanna Futures)AstraZeneca, Charlottesville area, VA | Under construction | $4.5B600 jobs |
| Clayton fill-finish facility (second)Novo Nordisk, Clayton, NC | Under construction | $4.1B1,000 jobs |
| Lehigh Valley pharmaceutical manufacturing facilityEli Lilly and Company, Fogelsville, PA | Announced | $3.5B850 jobs |
| Kenosha County injectable medicines manufacturing expansion (former Nexus Pharmaceuticals site)Eli Lilly and Company, Pleasant Prairie, WI | Announced | $3.0B750 jobs |
| Elkton Center of Excellence for Pharmaceutical Ingredients and Small Molecule ManufacturingMerck & Co. (MSD), Elkton, VA | Announced | $3.0B500 jobs |
| West Point vaccine and medicine manufacturing expansionMerck & Co., Inc., West Point, PA | Announced | $2.9Bjobs not stated |
| Houston (Generation Park) drug manufacturing campusBristol Myers Squibb, Houston, TX | Announced | $2.3B500 jobs |
| New Albany pharmaceutical manufacturing campusBayer, New Albany, OH | Announced | $2.2B600 jobs |
| Wilson biologics manufacturing campusJohnson & Johnson, Wilson, NC | Under construction | $2.0B420 jobs |
| Saratoga Springs drug manufacturing facilityRegeneron Pharmaceuticals, Inc., Saratoga Springs, NY | Announced | $2.0B1,000 jobs |
| Rock Hill plasma-derived medicines manufacturing siteOctapharma, Rock Hill, SC | Announced | $1.5B1,500 jobs |
| Durham pharmaceutical manufacturing campusAbbVie Inc., Durham, NC | Announced | $1.4B734 jobs |
| Holly Springs cell culture facility expansionFUJIFILM Diosynth Biotechnologies North Carolina, Inc., Holly Springs, NC | Announced | $1.2B680 jobs |
| Concord parenteral manufacturing plantEli Lilly and Company, Concord, NC | Announced | $1.0B589 jobs |
| Montgomery County next-generation cell therapy manufacturing facilityJohnson & Johnson, Lower Gwynedd Township, PA | Announced | $1.0B500 jobs |
| Williamsburg Township biotech manufacturing facilityLonza USA Inc., Williamsburg Township, OH | Announced | $1.0B650 jobs |
| Wilmington Biologics Center of ExcellenceMerck & Co., Inc., Wilmington, DE | Under construction | $1.0B500 jobs |
| De Soto vaccine manufacturing expansionMerck Animal Health, De Soto, KS | Announced | $895M200 jobs |
| Marietta vaccine and medicines site expansionGSK, Marietta, PA | Announced | $800M200 jobs |
| Upper Merion biopharmaceutical innovation and manufacturing hubGSK, Upper Merion Township, PA | Announced | $800M300 jobs |
| Research Triangle manufacturing expansionNovartis, Durham, NC | Under construction | $771M700 jobs |
| Hillsboro fill-finish manufacturing expansionGenentech (Roche), Hillsboro, OR | Under construction | $750M250 jobs |
| West Chester KwikPen manufacturing expansionNational Resilience, Inc. (with Eli Lilly and Company), West Chester, OH | Announced | $750M400 jobs |
| Frederick nucleic acid API manufacturing expansionAgilent Technologies, Frederick, CO | Under construction | $725M160 jobs |
| Holly Springs fill-finish manufacturing plantGenentech (Roche Group), Holly Springs, NC | Announced | $700M400 jobs |
| Manhattan biologics manufacturing plantScorpion Biological Services, Manhattan, KS | Announced | $650M500 jobs |
| Amgen North Carolina drug substance facilityAmgen, Holly Springs, NC | Operating | $550M355 jobs |
| Bellwether District radioisotope manufacturing facilityTerraPower Isotopes, Philadelphia, PA | Announced | $450M225 jobs |
| Muskegon Charter Township chromatography resin plantGlobal Life Sciences Solutions USA, Muskegon Charter Township, MI | Announced | $430M200 jobs |
| North Chicago API manufacturing expansion (two facilities)AbbVie, North Chicago, IL | Announced | $380M300 jobs |
| Amgen Ohio assembly and packaging plantAmgen, New Albany, OH | Operating | $365M400 jobs |
| Rockville cell therapy manufacturing facilityAstraZeneca, Rockville, MD | Operating(reported) | $300M150 jobs |
| Hopewell Campus oncology small-molecule plantBeOne Medicines US Manufacturing Co., Inc., Pennington (Hopewell Township), NJ | Announced | $300M120 jobs |
| College Station commercial biomanufacturing facility (expansion)FUJIFILM Diosynth Biotechnologies, College Station, TX | Announced | $300M150 jobs |
| Spokane sterile injectable fill-finish plant expansionJubilant HollisterStier, Spokane, WA | Operating | $285M200 jobs |
| Rockville biologics drug substance plant (acquired from GSK, expansion)Samsung Biologics, Rockville, MD | Announced | $280Mjobs not stated |
| Norton siRNA manufacturing plant expansionAlnylam Pharmaceuticals, Inc., Norton, MA | Under construction | $250Mjobs not stated |
| Logan bioprocessing products expansionHyClone Laboratories (Cytiva), Logan, UT | Announced | $231M396 jobs |
| Sanford contrast media manufacturing plant (first U.S. plant)Bracco Imaging, Sanford, NC | Announced | $230M200 jobs |
| Verona GMP drug manufacturing facility and lab campusArrowhead Pharmaceuticals, Inc., Verona, WI | Announced | $220M230 jobs |
| Columbus oral solid dose and nasal products expansionHikma Pharmaceuticals, Columbus, OH | Announced | $216M50 jobs |
| Albemarle County biopharmaceutical facility expansionAfton Scientific, Albemarle County, VA | Announced | $200M200 jobs |
| Albuquerque sterile fill-finish expansionCuria, Albuquerque, NM | Operating | $200M250 jobs |
| Madison iPSC manufacturing facility and headquartersFUJIFILM Cellular Dynamics, Madison, WI | Operating | $200Mjobs not stated |
| Fishers injectables manufacturing campus expansionINCOG BioPharma Services, Fishers, IN | Announced | $200Mjobs not stated |
| Sanford biologics manufacturing plant (Helix Innovation Park)Kyowa Kirin North America Manufacturing, LLC, Sanford, NC | Announced | $200M102 jobs |
| Whitestown radiopharmaceutical manufacturing facilityRayzeBio (Bristol Myers Squibb), Whitestown, IN | Announced | $173M100 jobs |
| Charles City API manufacturing expansionCambrex Charles City, Inc., Charles City, IA | Announced | $150M104 jobs |
| Elwood monoclonal antibody plant expansionElanco Animal Health Inc., Elwood, KS | Announced | $130M70 jobs |
| North Augusta peptide API plant expansionAmbioPharm, Inc., North Augusta, SC | Announced | $119M202 jobs |
| Henrietta pharmaceutical plant expansionUnither Pharmaceuticals, Henrietta, NY | Announced | $106M180 jobs |
| Prince William County biomanufacturing facilityATCC, Prince William County, VA | Announced | $55M75 jobs |
| Bedford injectables plant expansionHikma Pharmaceuticals, Bedford, OH | Announced | $51M300 jobs |
| Baltimore Bayview biologics plantSyngene USA Inc. (Syngene International), Baltimore, MD | Announced | $50M300 jobs |
| New Windsor pharmaceutical manufacturing facilityGaronit Pharmaceutical, Inc., New Windsor, NY | Announced | $46M100 jobs |
| Madison biologics development and manufacturing expansionCatalent, Madison, WI | Announced | $45M200 jobs |
| Cleveland pharmaceutical and OTC manufacturing site (former Beiersdorf plant)Formulated Solutions, Cleveland, TN | Announced | $44M524 jobs |
| Plano biomanufacturing facilityNTxBio, Plano, TX | Announced | $31M170 jobs |
| Northbridge pharmaceutical manufacturing facilityEyePoint Pharmaceuticals US Inc., Northbridge, MA | Announced | $30M45 jobs |
| Pekin IV solutions plantEpic Pharma Solutions Inc. (Epic Medical), Pekin, IL | Announced | $25M50 jobs |
| Wichita sterile health care products plant expansionFagron Sterile Services, Wichita, KS | Announced | $20M150 jobs |
| Frederick biologics manufacturing facility expansionAstraZeneca, Frederick, MD | Announced | —200 jobs |
| Gaithersburg clinical manufacturing facilityAstraZeneca, Gaithersburg, MD | Announced | —100 jobs |
| Wilson drug product manufacturing facility (second Wilson site)Johnson & Johnson, Wilson, NC | Announced | —500 jobs |
| Gaslight Square stem cell therapy manufacturing facilityNature Cell America (Nature Cell / Biostar), Baltimore, MD | Announced | —500 jobs |
Investment and job figures are as announced by the company or state, not achieved. Status comes from the latest dated milestone with a source.
Announcements by year
- 2021: 4
- 2022: 7
- 2023: 3
- 2024: 11
- 2025: 20
- 2026: 24