Chemicals manufacturers in South Carolina
South Carolina has 280 chemicals establishments employing 24,555 people (Census, 2023), and EPA's ECHO database lists 327 active chemicals facilities in the state. By employment it is South Carolina's number 5 manufacturing industry, and South Carolina ranks number 14 among states for it.
- NAICS subsector
- 325
- Chemical Manufacturing
- Establishments
- 280
- Census 2023
- Employees
- 24,555
- Census 2023
- In EPA records
- 327
- With a page here
- 11
- Revised
- November 11, 2026
Chemicals factories with a page
| Facility | What it makes (NAICS) | City |
|---|---|---|
| 3v Inc. | All Other Miscellaneous Chemical Product and Preparation Manufacturing | Georgetown |
| Alpek Polyester USA LLC - Columbia Site | Plastics Material and Resin Manufacturing | Gaston |
| Archroma US Inc Martin Plant | Synthetic Dye and Pigment Manufacturing | Martin |
| Auriga Polymers Inc | Plastics Material and Resin Manufacturing | Spartanburg |
| Bp Amoco Chemical Co - Cooper River Plant | Petrochemical Manufacturing | Wando |
| Dak Americas LLC | Plastics Material and Resin Manufacturing | Moncks Corner |
| Eastman Chemical Company Sc Operations | Plastics Material and Resin Manufacturing | Gaston |
| Invista S.a.r.l. | Plastics Material and Resin Manufacturing | Lugoff |
| Shaw Industries Group Inc Plant 8s | Artificial and Synthetic Fibers and Filaments Manufacturing | Columbia |
| Si Group Inc - Orangeburg Facility | All Other Basic Organic Chemical Manufacturing | Orangeburg |
| Westvaco Corp Polychemicals Dept | Cyclic Crude, Intermediate, and Gum and Wood Chemical Manufacturing | North Charleston |
These are the South Carolina chemicals facilities that report to EPA's Toxics Release Inventory. The other 316 in EPA records don't have a page yet.
What these factories make
- Plastics Material and Resin Manufacturing (NAICS 325211): 7 facilities
- Petrochemical Manufacturing (NAICS 325110): 4 facilities
- All Other Basic Organic Chemical Manufacturing (NAICS 325199): 4 facilities
- Artificial and Synthetic Fibers and Filaments Manufacturing (NAICS 325220): 4 facilities
- All Other Miscellaneous Chemical Product and Preparation Manufacturing (NAICS 325998): 2 facilities
- Cyclic Crude, Intermediate, and Gum and Wood Chemical Manufacturing (NAICS 325194): 2 facilities
- Synthetic Dye and Pigment Manufacturing (NAICS 325130): 1 facility
- Other Basic Inorganic Chemical Manufacturing (NAICS 325180): 1 facility
- Pharmaceutical Preparation Manufacturing (NAICS 325412): 1 facility
- Ethyl Alcohol Manufacturing (NAICS 325193): 1 facility
Where they cluster
Cities with the most active chemicals facilities in EPA records: Greenville (33), Spartanburg (19), Rock Hill (19), Columbia (15), Sumter (11).
Chemicals manufacturing across the US. Everything made in South Carolina.