| Saratoga Springs drug manufacturing facilityRegeneron Pharmaceuticals, Inc., Saratoga Springs, New York | November 13, 2025Announced | $2.0B | governor.ny.gov |
| Benson rare earth magnet factoryVulcan Elements Inc., Benson, North Carolina | November 18, 2025Announced | $918M | governor.nc.gov |
| Research Triangle manufacturing expansionNovartis, Durham, North Carolina | November 19, 2025Announced | $771M | governor.nc.gov |
| Buffalo powertrain plant expansion (hybrid engines and transaxles)Toyota Motor Manufacturing West Virginia, Buffalo, West Virginia | November 18, 2025Announced | $453M | governor.wv.gov |
| Gaffney Series 6 module finishing facilityFirst Solar, Inc., Gaffney, South Carolina | November 14, 2025Announced | $330M | governor.sc.gov |
| Project Ranger hypersonic weapons manufacturing campusCastelion, Rio Rancho, New Mexico | November 17, 2025Announced | $220M | edd.newmexico.gov |
| Georgetown hybrid-compatible engine machining line (expansion)Toyota Motor Manufacturing Kentucky, Georgetown, Kentucky | November 20, 2025Announced | $204M | kentucky.gov |
| Memphis large power transformer plant expansion (765kV)Hyosung HICO, Ltd., Memphis, Tennessee | November 12, 2025Announced | $157M | tn.gov |
| Lewistown production line expansionFirst Quality Retail Services, LLC, Lewistown, Pennsylvania | November 13, 2025Announced | $142M | pa.gov |
| Gastonia precast concrete plantFit Precast, Gastonia, North Carolina | November 18, 2025Announced | $102M | governor.nc.gov |
| Fremont data center infrastructure manufacturingBright Machines, Fremont, California | November 17, 2025Announced | $63M | business.ca.gov |
| Nashville automotive glass plant expansionCarlex Glass America, Nashville, Tennessee | November 19, 2025Announced | $55M | tn.gov |
| Torrance aerospace components factory expansionHadrian Automation, Inc., Torrance, California | November 17, 2025Announced | $52M | business.ca.gov |
| Muscatine condiments and sauces plant expansionKraft Heinz, Muscatine, Iowa | November 21, 2025Announced | $48M | opportunityiowa.gov |
| Rincon large power transformer plant expansionVirginia Transformer Corp. (Georgia Transformer), Rincon, Georgia | November 20, 2025Announced | $40M | georgia.org |
| Youngstown seamless pipe threading line expansionVallourec, Youngstown, Ohio | November 10, 2025Announced | $39M | jobsohio.com |
| Santa Rosa vitamins and supplements manufacturingBella Phytologic, Santa Rosa, California | November 17, 2025Announced | $33M | business.ca.gov |
| Roanoke County night vision plant expansionElbit Systems of America, Roanoke, Virginia | November 12, 2025Announced | $30M | governor.virginia.gov |
| Jacksonville heat transfer products plantCancoil USA, Jacksonville, Texas | November 20, 2025Announced | $28M | gov.texas.gov |
| Asheboro prefabricated MEP assembly plant expansionEnvironmental Air Systems, LLC (Comfort Systems USA), Asheboro, North Carolina | November 25, 2025Announced | $20M | commerce.nc.gov |
| Madera seaweed snack manufacturing facilityGimme Health Foods Inc, Madera, California | November 17, 2025Announced | $20M | business.ca.gov |
| Lexington oral pouch contract manufacturing plantWiJo Pouches North America, Inc., Lexington, South Carolina | November 25, 2025Announced | $14M | governor.sc.gov |
| Long Beach satellite manufacturing expansionTrue Anomaly, Long Beach, California | November 17, 2025Announced | $13M | business.ca.gov |
| Suwanee electrical equipment facilitySocomec, Suwanee, Georgia | November 12, 2025Announced | $10M | georgia.org |
| James City County power distribution equipment plantCEL Critical Power, Williamsburg, Virginia | November 5, 2025Announced | $5M | governor.virginia.gov |
| Clark County manufacturing and distribution operationWelspun USA, Inc., Las Vegas area, Nevada | November 10, 2025Announced | $5M | goed.nv.gov |
| Colorado Springs LiFi manufacturing facilityTerra Ferma, Colorado Springs, Colorado | November 19, 2025Announced | $1M | oedit.colorado.gov |
| Frederick biologics manufacturing facility expansionAstraZeneca, Frederick, Maryland | November 21, 2025Announced | — | governor.maryland.gov |
| Gaithersburg clinical manufacturing facilityAstraZeneca, Gaithersburg, Maryland | November 21, 2025Announced | — | governor.maryland.gov |
| Frederick bakery expansion (new 176,000 sq ft facility)Bakery de France (with La Lorraine Bakery Group), Frederick, Maryland | November 3, 2025Announced | — | commerce.maryland.gov |
| Gaslight Square stem cell therapy manufacturing facilityNature Cell America (Nature Cell / Biostar), Baltimore, Maryland | November 18, 2025Announced | — | commerce.maryland.gov |