| Oklahoma primary aluminum smelterEmirates Global Aluminium (60%) / Century Aluminum (40%), Inola, Oklahoma | May 16, 2025Announced | $4.0B | okcommerce.gov |
| Lancaster hydrogen fuel production facilityElement Lancaster 1 LLC, Lancaster, California | May 1, 2025Announced | $1.9B | business.ca.gov |
| Shoal River gas turbine engine manufacturing facilityWilliams International, Crestview, Florida | May 29, 2025Announced | $1.0B | flgov.com |
| De Soto vaccine manufacturing expansionMerck Animal Health, De Soto, Kansas | May 8, 2025Announced | $895M | kansascommerce.gov |
| Tonawanda Propulsion plant expansion (V-8 engine)General Motors, Tonawanda, New York | May 27, 2025Announced | $888M | governor.ny.gov |
| Warren personal care products plantKimberly-Clark Corporation, Warren, Ohio | May 1, 2025Announced | $800M | jobsohio.com |
| Holly Springs fill-finish manufacturing plantGenentech (Roche Group), Holly Springs, North Carolina | May 12, 2025Announced | $700M | governor.nc.gov |
| Indianapolis diagnostics manufacturing hub expansion (CGM)Roche Diagnostics, Indianapolis, Indiana | May 12, 2025Announced | $550M | diagnostics.roche.com |
| Shelby aerospace coatings and sealants manufacturing centerPPG, Shelby, North Carolina | May 8, 2025Announced | $380M | governor.nc.gov |
| MidAmerica Industrial Park ammunition plantCBC Global Ammunition (CBC USA), Pryor, Oklahoma | May 12, 2025Announced | $300M | oklahoma.gov |
| Clarendon County wood fiberboard plantHomanit, Alcolu, South Carolina | May 21, 2025Announced | $250M | governor.sc.gov |
| Goldsboro second transformer plant (expansion)Prolec-GE Waukesha, Inc., Goldsboro, North Carolina | May 14, 2025Announced | $140M | governor.nc.gov |
| Edison food packaging manufacturing and distribution facilityHotpack Global, Edison, New Jersey | May 2, 2025Announced | $100M | nj.gov |
| St. Joseph bacon plant expansionDaily's Premium Meats, St. Joseph, Missouri | May 12, 2025Announced | $95M | oembed-ded.mo.gov |
| Bell food manufacturing expansionLegendary Foods LLC, Bell, California | May 1, 2025Announced | $70M | business.ca.gov |
| Charlotte generator enclosure plantAVL USA, Inc. (AVL Manufacturing), Charlotte, North Carolina | May 22, 2025Announced | $56M | governor.nc.gov |
| Goodyear industrial enclosures manufacturing facilityGTI Energy (GTI Fabrication), Goodyear, Arizona | May 20, 2025Announced | $53M | azcommerce.com |
| Chaska clinical diagnostics manufacturing expansionBeckman Coulter Inc., Chaska, Minnesota | May 8, 2025Announced | $50M | mn.gov |
| Ridgeway copper wire plantMega Metal Inc., Ridgeway, South Carolina | May 13, 2025Announced | $34M | governor.sc.gov |
| Plano biomanufacturing facilityNTxBio, Plano, Texas | May 14, 2025Announced | $31M | gov.texas.gov |
| Macon frozen foods plant expansionConagra Brands, Macon, Missouri | May 9, 2025Announced | $29M | oembed-ded.mo.gov |
| Portland wire mesh panel plant (relocation from Chicago area)Aspen Guard (Troax Group), Portland, Tennessee | May 1, 2025Announced | $23M | tn.gov |
| Richmond ice cream sandwich production facility and headquartersNightingale Ice Cream Sandwiches, Richmond, Virginia | May 29, 2025Announced | $6M | governor.virginia.gov |
| Fort Ritchie medical components plantSJ Incorporation, Cascade, Maryland | May 22, 2025Announced | — | commerce.maryland.gov |